Cortisol Rhythm and Adrenal Testing: Beyond the Morning Value
Cortisol is the principal glucocorticoid, essential for gluconeogenesis, blood pressure, immune modulation and the stress response. Both excess (Cushing's) and deficiency (Addison's) are serious; more common in everyday practice is dysregulated rhythm — a flattened diurnal curve associated with chronic stress, poor sleep and metabolic disease.